Metabolism is a highly regulated system of biological processes responsible for the construction (anabolism) and destruction (catabolism) of molecules (e.g., carbohydrates, lipids, proteins, nucleotides) for energy, managing homeostasis through cellular maintenance and energy regulation. Disruption of metabolic processes can lead to a host of diseases including cancer, diabetes, cardiovascular disease, and metabolic syndromes. Cell Signaling Technology (CST) provides high-quality antibodies and assays to support the interrogation of cellular regulation and metabolic pathways.
Modulation of metabolism is critical for normal cellular homeostasis while abnormal metabolic signaling can lead to serious disorders such as cancer. CST is the world's leading provider for metabolic signaling antibodies including those for the PI3K, Akt, mTOR, and AMPK pathways, which play critical roles in cancer biology. Partner with CST to uncover new insights into the dysregulation of cellular signaling and inform therapeutic development.
Carbohydrates, insulin, and lipids are some of the many components that maintain cellular homeostasis. Variations in biochemical metabolism can trigger severe diseases such as diabetes and cancer. CST offers a variety of antibodies to interrogate the effects of alterations in these physiologically important chemical reactions.
Autophagy is a catabolic process that creates energy during times of nutritional scarcity and acts as an intracellular quality control to clear damaged organelles and pathogens. This process involves capturing intracellular contents into a double-membrane structure, termed the autophagosome, which is delivered to the lysosome for degradation. Errors in the process of autophagy can result in pathophysiological conditions including cancer, metabolic diseases, neurodegeneration, and innate immunity. To help elucidate mechanisms of autophagy, CST offers a diverse selection of high-quality antibodies.
Accurately measure key metabolic parameters using our cellular assays and assorted antibody kits for efficient, convenient, and cost-effective measurements. Partner with CST to investigate the complexities of metabolism and achieve a more complete understanding of metabolic activity in your area of research.