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Cell Biology

Cell Biology

Cell biology research seeks to understand all aspects of cell growth, survival, and death in the contexts of both health and disease. Understanding the complex and dynamic cellular landscape can provide insights into healthy and disease states. Cell Signaling Technology (CST) provides a diverse and comprehensive catalog of rigorously tested and validated products to generate robust and reliable data and support your research into all aspects of cell biology.

Cellular Signaling

Cells respond to a multitude of signals in the extracellular environment, often by activating intracellular signaling pathways that elicit changes in cell function or behavior. These signaling pathways may be activated in response to growth factors, cytokines, or other signaling molecules, leading to intracellular activation of kinase pathways. CST offers a comprehensive portfolio of the highest quality products to interrogate molecular signaling networks.

Cell Death and Viability

Understanding the mechanisms that cause cell death is a critical aspect of cell biology, as many diseases involve aberrant regulation of cell death mechanisms. CST offers a variety of assays and reagents designed to enable evaluations of cell viability and cell death.

Cell Cycle/Proliferation

Cell proliferation is required for tissue growth, development, maintenance, and repair. Disruptions to the cell cycle that governs proliferation are a root cause of many diseases, most notably cancer. CST has a diverse catalog of antibodies and assays to study cell cycle progression and checkpoint control.

Cytoskeleton and Extracellular Matrix

Studying the dynamic nature and contribution of cytoskeletal and ECM proteins to cell structure and motility can provide insight into cell migration in the tumor microenvironment, metastasis, and neurodegeneration. CST offers a range of validated antibodies for immunohistochemistry (IHC) and immunofluorescence (IF) to visualize both intracellular and extracellular structures.

Protein Translation, Stability, and Degradation

Maintaining homeostasis requires cells to regulate the translation, stability and degradation of thousands of proteins simultaneously. CST offers a variety of validated antibodies to investigate how protein translation, stabilization, and degradation contribute to the pathogenesis of certain diseases.

Vesicles and Protein Trafficking

Vesicle and protein trafficking play an integral role in a variety of cellular signaling pathways involved in basic biological functions like protein maturation, transport, and secretion – the disruption of which can cause many different disorders. Choose the right antibodies for your research on intracellular and extracellular transport pathways.

Cell Death and Viability Assays

Obtain precise data by using one of the many high-quality assays that CST has to offer for efficient, convenient, and cost-effective measurements of cell death and viability.

Cell Cycle and Proliferation Assays

CST offers high-quality, reliable, and sensitive assays to save you time in the evaluation of cell cycle regulation through monitoring DNA repair mechanisms, cell proliferation, and checkpoint control.

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